Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice

<p>Abstract</p> <p>Background</p> <p>Evidence suggests that dendritic cells accumulate in the lungs of COPD patients and correlate with disease severity. We investigated the importance of IL-1R1 and its ligands IL-1α and β to dendritic cell accumulation and maturation i...

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Bibliographic Details
Main Authors: Botelho Fernando M, Nikota Jake K, Bauer Carla MT, Morissette Mathieu C, Iwakura Yoichiro, Kolbeck Roland, Finch Donna, Humbles Alison A, Stämpfli Martin R
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Respiratory Research
Subjects:
Cigarette smoke
Dendritic cells
T cells
CCL20
Mice
Online Access:http://respiratory-research.com/content/13/1/81

Internet

http://respiratory-research.com/content/13/1/81

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