Orexin receptor antagonist increases fat oxidation and suppresses protein catabolism during sleep in humans

Orexin receptor antagonist increases fat oxidation and suppresses protein catabolism during sleep in humans

Summary: Suvorexant is an orexin receptor antagonist that targets the wake-promoting system. Orexin is also known to regulate energy metabolism in rodents, but its role in humans remains largely unknown. Here, we assessed the effect of suvorexant (20 mg) on energy metabolism during sleep and shortly...

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Bibliographic Details
Main Authors: Insung Park, Rikako Yoshitake, Kazuki Kioka, Asuka Ishihara, Katsuhiko Yajima, Fusae Kawana, Toshio Kokubo, Ichiyo Matsuzaki, Takashi Kanbayashi, Masashi Yanagisawa, Kumpei Tokuyama
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:iScience
Subjects:
Health sciences
Human metabolism
Physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224014378

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224014378

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