Notch, SUMOylation, and ESR-Mediated Signalling Are the Main Molecular Pathways Showing Significantly Different Epimutation Scores between Expressing or Not Oestrogen Receptor Breast Cancer in Three Public EWAS Datasets

Oestrogen receptor expression in breast cancer (BC) cells is a marker of high cellular differentiation and allows the identification of two BC groups (ER-positive and ER-negative) that, although not completely homogeneous, differ in biological characteristics, clinical behaviour, and therapeutic opt...

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Bibliographic Details
Main Authors: Luigi Corsaro, Vincenzo Sandro Gambino
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/16/4109