Design and Preparation of a Multimeric Self-Cleaving Hammerhead Ribozyme
The activity of a ribozyme can be impaired by additional sequences at the 5′ and 3′ termini of the catalytic sequence. To approach this problem, a system was designed that minimizes sequences upstream and downstream from active regions of a hammerhead ribozyme and allows delivery of a large number o...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
1997-02-01
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| Series: | BioTechniques |
| Online Access: | https://www.future-science.com/doi/10.2144/97222rr03 |