Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.

Mutation Analysis of the RAD51C and RAD51D Genes in High-Risk Ovarian Cancer Patients and Families from the Czech Republic.

Recent studies have conferred that the RAD51C and RAD51D genes, which code for the essential proteins involved in homologous recombination, are ovarian cancer (OC) susceptibility genes that may explain genetic risks in high-risk patients. We performed a mutation analysis in 171 high-risk BRCA1 and B...

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Bibliographic Details
Main Authors: Marketa Janatova, Jana Soukupova, Jana Stribrna, Petra Kleiblova, Michal Vocka, Petra Boudova, Zdenek Kleibl, Petr Pohlreich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4461297?pdf=render

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http://europepmc.org/articles/PMC4461297?pdf=render

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