Plasmonic nano-aperture label-free imaging of single small extracellular vesicles for cancer detection

Abstract Background Small extracellular vesicle (sEV) analysis can potentially improve cancer detection and diagnostics. However, this potential has been constrained by insufficient sensitivity, dynamic range, and the need for complex labeling. Methods In this study, we demonstrate the combination o...

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Bibliographic Details
Main Authors: Nareg Ohannesian, Mohammad Sadman Mallick, Jianzhong He, Yawei Qiao, Nan Li, Simona F. Shaitelman, Chad Tang, Eileen H. Shinn, Wayne L. Hofstetter, Alexei Goltsov, Manal M. Hassan, Kelly K. Hunt, Steven H. Lin, Wei-Chuan Shih
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00514-x