The Pharmacochaperone Activity of Quinine on Bitter Taste Receptors.

Bitter taste is one of the five basic taste sensations which is mediated by 25 bitter taste receptors (T2Rs) in humans. The mechanism of bitter taste signal transduction is not yet elucidated. The cellular processes underlying T2R desensitization including receptor internalization, trafficking and d...

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Bibliographic Details
Main Authors: Jasbir D Upadhyaya, Raja Chakraborty, Feroz A Shaik, Appalaraju Jaggupilli, Rajinder P Bhullar, Prashen Chelikani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0156347&type=printable