Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i>
The phytochemical study of <i>Wisteria sinensis</i> (Sims) DC. (Fabaceae), commonly known as the Chinese Wisteria, led to the isolation of seven oleanane-type glycosides from an aqueous-ethanolic extract of the roots. Among the seven isolated saponins, two have never been reported before...
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MDPI AG
2022-11-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/22/7866 |
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| author | Samir Hobloss Antoine Bruguière David Pertuit Tomofumi Miyamoto Chiaki Tanaka Christine Belloir Marie-Aleth Lacaille-Dubois Loïc Briand Anne-Claire Mitaine-Offer |
| author_facet | Samir Hobloss Antoine Bruguière David Pertuit Tomofumi Miyamoto Chiaki Tanaka Christine Belloir Marie-Aleth Lacaille-Dubois Loïc Briand Anne-Claire Mitaine-Offer |
| author_sort | Samir Hobloss |
| collection | DOAJ |
| description | The phytochemical study of <i>Wisteria sinensis</i> (Sims) DC. (Fabaceae), commonly known as the Chinese Wisteria, led to the isolation of seven oleanane-type glycosides from an aqueous-ethanolic extract of the roots. Among the seven isolated saponins, two have never been reported before: 3-<i>O</i>-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl-22-<i>O</i>-acetylolean-12-ene-3β,16β,22β,30-tetrol, and 3-<i>O</i>-β-D-xylopyranosyl-(1→2)-β-D-glucuronopyranosylwistariasapogenol A. Based on the close structures between the saponins from <i>W. sinensis</i>, and the glycyrrhizin from licorice, the stimulation of the sweet taste receptor TAS1R2/TAS1R3 by these glycosides was evaluated. |
| first_indexed | 2024-03-09T18:07:06Z |
| format | Article |
| id | doaj.art-92fad64540954c50a4f3ccea709da4e0 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T18:07:06Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-92fad64540954c50a4f3ccea709da4e02023-11-24T09:22:29ZengMDPI AGMolecules1420-30492022-11-012722786610.3390/molecules27227866Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i>Samir Hobloss0Antoine Bruguière1David Pertuit2Tomofumi Miyamoto3Chiaki Tanaka4Christine Belloir5Marie-Aleth Lacaille-Dubois6Loïc Briand7Anne-Claire Mitaine-Offer8Centre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceGraduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, JapanGraduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, JapanCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceCentre des Sciences du Goût et de l’Alimentation, CNRS, INRAE, Institut Agro, Université de Bourgogne, Franche-Comté, 21000 Dijon, FranceThe phytochemical study of <i>Wisteria sinensis</i> (Sims) DC. (Fabaceae), commonly known as the Chinese Wisteria, led to the isolation of seven oleanane-type glycosides from an aqueous-ethanolic extract of the roots. Among the seven isolated saponins, two have never been reported before: 3-<i>O</i>-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranosyl-(1→2)-β-D-glucuronopyranosyl-22-<i>O</i>-acetylolean-12-ene-3β,16β,22β,30-tetrol, and 3-<i>O</i>-β-D-xylopyranosyl-(1→2)-β-D-glucuronopyranosylwistariasapogenol A. Based on the close structures between the saponins from <i>W. sinensis</i>, and the glycyrrhizin from licorice, the stimulation of the sweet taste receptor TAS1R2/TAS1R3 by these glycosides was evaluated.https://www.mdpi.com/1420-3049/27/22/7866<i>Wisteria sinensis</i>Fabaceaetriterpene glycosidessweet tasteTAS1R2/TAS1R3 |
| spellingShingle | Samir Hobloss Antoine Bruguière David Pertuit Tomofumi Miyamoto Chiaki Tanaka Christine Belloir Marie-Aleth Lacaille-Dubois Loïc Briand Anne-Claire Mitaine-Offer Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> Molecules <i>Wisteria sinensis</i> Fabaceae triterpene glycosides sweet taste TAS1R2/TAS1R3 |
| title | Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> |
| title_full | Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> |
| title_fullStr | Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> |
| title_full_unstemmed | Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> |
| title_short | Activation of a Sweet Taste Receptor by Oleanane-Type Glycosides from <i>Wisteria sinensis</i> |
| title_sort | activation of a sweet taste receptor by oleanane type glycosides from i wisteria sinensis i |
| topic | <i>Wisteria sinensis</i> Fabaceae triterpene glycosides sweet taste TAS1R2/TAS1R3 |
| url | https://www.mdpi.com/1420-3049/27/22/7866 |
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