Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN

Proteomic signature of tubulointerstitial tissue predicts prognosis in IgAN

Abstract Background IgA nephropathy (IgAN) is associated with a significant risk of progression to kidney failure. Tubular atrophy is an established important risk factor for progressive disease, but few studies have investigated tubulointerstitial molecular markers and mechanisms of progression in...

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Bibliographic Details
Main Authors: Flavia Teodora Ioana Paunas, Kenneth Finne, Sabine Leh, Hans-Peter Marti, Frode Berven, Bjørn Egil Vikse
Format: Article
Language:English
Published: BMC 2022-03-01
Series:BMC Nephrology
Subjects:
IgA nephropathy
ESRD
Formalin-fixed paraffin embedded kidney biopsy tissue
Liquid chromatography–tandem mass spectrometry
Proteomic analyses
Tubulointerstitium
Online Access:https://doi.org/10.1186/s12882-022-02736-4

Internet

https://doi.org/10.1186/s12882-022-02736-4

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