The role of alkyl chain length in the melt and solution crystallization of paliperidone aliphatic prodrugs

Fatty acid-derivative prodrugs have been utilized extensively to improve the physicochemical, biopharmaceutical and pharmacokinetic properties of active pharmaceutical ingredients. However, to our knowledge, the crystallization behavior of prodrugs modified with different fatty acids has not been ex...

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Bibliographic Details
Main Authors: An Chen, Peishan Cai, Yayun Peng, Minshan Guo, Yuan Su, Ting Cai
Format: Article
Language:English
Published: International Union of Crystallography 2024-01-01
Series:IUCrJ
Subjects:
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252523009582