Evaluation of Tumor Budding in Primary Colorectal Cancer and Corresponding Liver Metastases Based on H&E and Pancytokeratin Staining

In colorectal cancer, tumor budding is associated with tumor progression and represents an additional prognostic factor in the TNM classification. Tumor buds can be found at the invasive front (peritumoral budding; PTB) and in the tumor center (intratumoral budding; ITB) of primary tumors. Previous...

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Bibliographic Details
Main Authors: Annika Blank, Carla Schenker, Heather Dawson, Guido Beldi, Inti Zlobec, Alessandro Lugli
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00247/full