Engineering of Shikimate Pathway and Terminal Branch for Efficient Production of L-Tryptophan in <i>Escherichia coli</i>

L-tryptophan (L-trp), produced through bio-manufacturing, is widely used in the pharmaceutical and food industries. Based on the previously developed L-trp-producing strain, this study significantly improved the titer and yield of L-trp, through metabolic engineering of the shikimate pathway and the...

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Bibliographic Details
Main Authors: Shuai Liu, Bing-Bing Wang, Jian-Zhong Xu, Wei-Guo Zhang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/14/11866