Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms

Abstract Background Colistin is used against multi-drug resistant pathogens, yet resistance emerges through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes involved in lipopolysaccharide synthesis (i.e. mgrB, phoPQ, pmrCAB). Phenotypic susceptibility testing is challen...

Full description

Bibliographic Details
Main Authors: Diana Albertos Torres, Helena M. B. Seth-Smith, Nicole Joosse, Claudia Lang, Olivier Dubuis, Magdalena Nüesch-Inderbinen, Vladimira Hinic, Adrian Egli
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Microbiology
Subjects:
Colistin
Resistance
Antimicrobial susceptibility testing
WGS
Antimicrobial resistance genes
Online Access:https://doi.org/10.1186/s12866-021-02388-8

Internet

https://doi.org/10.1186/s12866-021-02388-8

Similar Items