The emerging role of autophagy and mitophagy in tauopathies: From pathogenesis to translational implications in Alzheimer’s disease

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease, affecting more than 55 million individuals worldwide in 2021. In addition to the “amyloid hypothesis,” an increasing number of studies have demonstrated that phosphorylated tau plays an important role in AD pathogenesis. Both...

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Bibliographic Details
Main Authors: Xiaolan Liu, Meng Ye, Liang Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1022821/full