Leaf hydroalcoholic extract and oleoresin from Copaifera multijuga control Toxoplasma gondii infection in human trophoblast cells and placental explants from third-trimester pregnancy

Leaf hydroalcoholic extract and oleoresin from Copaifera multijuga control Toxoplasma gondii infection in human trophoblast cells and placental explants from third-trimester pregnancy

The conventional treatment of congenital toxoplasmosis is mainly based on the combination of sulfadiazine and pyrimethamine. However, therapy with these drugs is associated with severe side effects and resistance, requiring the study of new therapeutic strategies. There are currently many studies wi...

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Bibliographic Details
Main Authors: Aryani Felixa Fajardo Martínez, Samuel Cota Teixeira, Guilherme de Souza, Alessandra Monteiro Rosini, Joed Pires de Lima Júnior, Gabriel Nogueira Melo, Kelvin Orlando Espinoza Blandón, Angelica Oliveira Gomes, Sergio Ricardo Ambrósio, Rodrigo Cassio Sola Veneziani, Jairo Kenupp Bastos, Carlos Henrique Gomes Martins, Eloisa Amália Vieira Ferro, Bellisa Freitas Barbosa
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Toxoplasma gondii
congenital toxoplasmosis (CT)
trophoblast
Copaifera multijuga
hydroalcoholic extract
oleoresin
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1113896/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2023.1113896/full

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