β-Funaltrexamine Displayed Anti-Inflammatory and Neuroprotective Effects in Cells and Rat Model of Stroke

β-Funaltrexamine Displayed Anti-Inflammatory and Neuroprotective Effects in Cells and Rat Model of Stroke

Chronic treatment involving opioids exacerbates both the risk and severity of ischemic stroke. We have provided experimental evidence showing the anti-inflammatory and neuroprotective effects of the μ opioid receptor antagonist β-funaltrexamine for neurodegenerative diseases in rat neuron/glia cultu...

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Bibliographic Details
Main Authors: Chih-Cheng Wu, Cheng-Yi Chang, Kuei-Chung Shih, Chih-Jen Hung, Ya-Yu Wang, Shih-Yi Lin, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Wen-Yi Wang, Chun-Jung Chen
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
microglia polarization
neuroinflammation
opioid
stroke
Online Access:https://www.mdpi.com/1422-0067/21/11/3866

Internet

https://www.mdpi.com/1422-0067/21/11/3866

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