Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5

Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5

ABSTRACT Urinary tract infection (UTI) caused by uropathogenic Escherichia coli (UPEC) engages interleukin-10 (IL-10) as an early innate immune response to regulate inflammation and promote the control of bladder infection. However, the mechanism of engagement of innate immunity by UPEC that leads t...

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Bibliographic Details
Main Authors: Dhruba Acharya, Matthew J. Sullivan, Benjamin L. Duell, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michelle N. Chamoun, Asha Kakkanat, Debasish Chattopadhyay, Michael Crowley, David K. Crossman, Mark A. Schembri, Glen C. Ulett
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSphere
Subjects:
flagella
urinary tract infection
uropathogenic Escherichia coli
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00545-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00545-19

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