Ratio Imaging of Enzyme Activity Using Dual Wavelength Optical Reporters
The design of near-infrared fluorescent (NIRF) probes that are activated by specific proteases has, for the first time, allowed enzyme activity to be imaged in vivo. In the current study, we report on a method of imaging enzyme activity using two fluorescent probes that, together, provide improved q...
Main Authors: | Moritz F. Kircher, Lee Josephson, Ralph Weissleder |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2002-04-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.1162/15353500200201124 |
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