Atopic dermatitis-associated genetic variants regulate LOC100294145 expression implicating interleukin-27 production and type 1 interferon signaling

Atopic dermatitis-associated genetic variants regulate LOC100294145 expression implicating interleukin-27 production and type 1 interferon signaling

Background: Atopic dermatitis (AD) is a complex inflammatory disease with a strong genetic component. A singular approach of genome wide association studies (GWAS) can identify AD-associated genetic variants, but is unable to explain their functional relevance in AD. This study aims to characterize...

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Bibliographic Details
Main Authors: Wei Yi Teo, BSc (Hons), Yi Ying Eliza Lim, BSc (Hons), Yang Yie Sio, PhD, Yee-How Say, PhD, Kavita Reginald, PhD, Fook Tim Chew, PhD
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:World Allergy Organization Journal
Subjects:
Atopic dermatitis
Genome-wide association study
Long non-coding RNA
Mendelian randomization
Multi-omics
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455123001308

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http://www.sciencedirect.com/science/article/pii/S1939455123001308

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