Accurate prediction of protein torsion angles using evolutionary signatures and recurrent neural network
Abstract The amino acid sequence of a protein contains all the necessary information to specify its shape, which dictates its biological activities. However, it is challenging and expensive to experimentally determine the three-dimensional structure of proteins. The backbone torsion angles play a cr...
Main Authors: | Yong-Chang Xu, Tian-Jun ShangGuan, Xue-Ming Ding, Ngaam J. Cheung |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-10-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-00477-2 |
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