A mathematical model exhibiting the effect of DNA methylation on the stability boundary in cell-fate networks

Cell-fate networks are traditionally studied within the framework of gene regulatory networks. This paradigm considers only interactions of genes through expressed transcription factors and does not incorporate chromatin modification processes. This paper introduces a mathematical model that seamles...

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Bibliographic Details
Main Authors: Tianchi Chen, M. Ali Al-Radhawi, Eduardo D. Sontag
Format: Article
Language:English
Published: Taylor & Francis Group 2021-04-01
Series:Epigenetics
Subjects:
Online Access:http://dx.doi.org/10.1080/15592294.2020.1805686