Label-Free Detection of the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein at Physiologically Relevant Concentrations Using Surface-Enhanced Raman Spectroscopy

Label-Free Detection of the Receptor-Binding Domain of the SARS-CoV-2 Spike Glycoprotein at Physiologically Relevant Concentrations Using Surface-Enhanced Raman Spectroscopy

Surface-enhanced Raman scattering (SERS) spectroscopy is a surface- or cavity-enhanced variant of Raman scattering spectroscopy that allows the detection of analytes with a sensitivity down to single molecules. This method involves the use of SERS-active surfaces or cavities capable of concentrating...

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Bibliographic Details
Main Authors: Andrey K. Sarychev, Alyona Sukhanova, Andrey V. Ivanov, Igor V. Bykov, Nikita V. Bakholdin, Daria V. Vasina, Vladimir A. Gushchin, Artem P. Tkachuk, Galina Nifontova, Pavel S. Samokhvalov, Alexander Karaulov, Igor Nabiev
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biosensors
Subjects:
SARS-CoV-2
S glycoprotein
RBD
surface-enhanced Raman spectroscopy
Raman spectroscopy
SERS
Online Access:https://www.mdpi.com/2079-6374/12/5/300

Internet

https://www.mdpi.com/2079-6374/12/5/300

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