AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis

AdpAlin, a Pleiotropic Transcriptional Regulator, Is Involved in the Cascade Regulation of Lincomycin Biosynthesis in Streptomyces lincolnensis

Lincomycin is one of the most important antibiotics in clinical practice. To further understand the regulatory mechanism on lincomycin biosynthesis, we investigated a pleiotropic transcriptional regulator AdpAlin in the lincomycin producer Streptomyces lincolnensis NRRL 2936. Deletion of adpAlin (wh...

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Bibliographic Details
Main Authors: Yajing Kang, Yingying Wang, Bingbing Hou, Ruida Wang, Jiang Ye, Xiaoyu Zhu, Haizhen Wu, Huizhan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Microbiology
Subjects:
AdpA
lincomycin
Streptomyces lincolnensis
transcriptional regulator
cascade regulation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02428/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02428/full

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