Engineered M2a macrophages for the treatment of osteoarthritis

BackgroundMacrophage is a central regulator of innate immunity. Its M2 subsets, such as interstitial synovial macrophages, have been found to play critical roles in suppressing chronic inflammation and maintaining homeostasis within the joint. These macrophages have great potential as a disease-modi...

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Bibliographic Details
Main Authors: Chi Liang, Song Wu, Guang Xia, Junjie Huang, Zi Wen, Wenxiu Zhang, Xu Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054938/full