New Caffeine Derivatives as Multitarget Agents for the Therapy of Alzheimer’s Disease

In this work we present the microwave-assisted synthesis and in vitro acetylcholinesterase inhibition of a series of new caffeine derivatives. The design of these new compounds was inspired by the caffeine–pyrrolidine hybrids that act as AChE inhibitors and nAChR activators, previously reported by o...

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Bibliographic Details
Main Authors: Brunella Biscussi, Ana Paula Murray
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/12/1/62