Decoupled neoantigen cross-presentation by dendritic cells limits anti-tumor immunity against tumors with heterogeneous neoantigen expression
Cancer immunotherapies, in particular checkpoint blockade immunotherapy (CBT), can induce control of cancer growth, with a fraction of patients experiencing durable responses. However, the majority of patients currently do not respond to CBT and the molecular determinants of resistance have not been...
| Հիմնական հեղինակներ: | , , , , , , , , , , |
|---|---|
| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
eLife Sciences Publications Ltd
2023-08-01
|
| Շարք: | eLife |
| Խորագրեր: | |
| Առցանց հասանելիություն: | https://elifesciences.org/articles/85263 |