Targeting chondroitinase ABC to axons enhances the ability of chondroitinase to promote neurite outgrowth and sprouting.

<h4>Background</h4>There is currently no effective treatment for promoting regeneration of injured nerves in patients who have sustained injury to the central nervous system such as spinal cord injury. Chondroitinase ABC is an enzyme, which promotes neurite outgrowth and regeneration. It...

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Bibliographic Details
Main Authors: Priscilla Day, Nuno Alves, Esther Daniell, Debayan Dasgupta, Rosalie Ogborne, Ashley Steeper, Mansoor Raza, Clare Ellis, James Fawcett, Roger Keynes, Elizabeth Muir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221851