Recent progress in the racemic and enantioselective synthesis of monofluoroalkene-based dipeptide isosteres

Monofluoroalkenes are fluorinated motifs that can be used to replace amide bonds. In order to be incorporated into peptides, it is normally necessary to first synthesize a dipeptide where the amide bond has been replaced with a monofluoroalkene. In that context, this review will present the racemic...

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Bibliographic Details
Main Authors: Myriam Drouin, Jean-François Paquin
Format: Article
Language:English
Published: Beilstein-Institut 2017-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.13.262