CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin

CB1 cannabinoid receptor in SF1-expressing neurons of the ventromedial hypothalamus determines metabolic responses to diet and leptin

Metabolic flexibility allows rapid adaptation to dietary change, however, little is known about the CNS mechanisms regulating this process. Neurons in the hypothalamic ventromedial nucleus (VMN) participate in energy balance and are the target of the metabolically relevant hormone leptin. Cannabinoi...

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Bibliographic Details
Main Authors: Pierre Cardinal, Caroline André, Carmelo Quarta, Luigi Bellocchio, Samantha Clark, Melissa Elie, Thierry Leste-Lasserre, Marlene Maitre, Delphine Gonzales, Astrid Cannich, Uberto Pagotto, Giovanni Marsicano, Daniela Cota
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Molecular Metabolism
Subjects:
CB1 receptor
Endocannabinoid
Ventromedial nucleus
Hypothalamus
Obesity
Leptin
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877814001306

Internet

http://www.sciencedirect.com/science/article/pii/S2212877814001306

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