G×G×E for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity.

Dietary restriction (DR) is the most consistent means of extending longevity in a wide range of organisms. A growing body of literature indicates that mitochondria play an important role in longevity extension by DR, but the impact of mitochondrial genotypes on the DR process have received little at...

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Bibliographic Details
Main Authors: Chen-Tseh Zhu, Paul Ingelmo, David M Rand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4022469?pdf=render