Cmarr/miR-540-3p axis promotes cardiomyocyte maturation transition by orchestrating Dtna expression

The immature phenotype of embryonic stem cell-derived cardiomyocytes (ESC-CMs) limits their application. However, the molecular mechanisms of cardiomyocyte maturation remain largely unexplored. This study found that overexpression of long noncoding RNA (lncRNA)-Cmarr, which was highly expressed in c...

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Bibliographic Details
Main Authors: Yukang Wu, Xudong Guo, Tong Han, Ke Feng, Peng Zhang, Yanxin Xu, Yiwei Yang, Yuchen Xia, Yang Chen, Jiajie Xi, Huangtian Yang, Xiaoping Wan, Jiuhong Kang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122001913