Protective effects of safranal on diabetic retinopathy in human microvascular endothelial cells and related pathways analyzed with transcriptome sequencing

Protective effects of safranal on diabetic retinopathy in human microvascular endothelial cells and related pathways analyzed with transcriptome sequencing

AimTo determine the effect of safranal on diabetic retinopathy in vitro and its possible mechanisms.MethodsWe used human retinal microvascular endothelial cells (HRMECs) to test the influence of safranal in vitro. High glucose damage was established and an safranal was tested at various concentratio...

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Bibliographic Details
Main Authors: Qin Xiao, Yao-Yao Sun, Zhan-Jun Lu, Shan-shan Li, Riguga Su, Wen-Lin Chen, Lin-Lin Ran, Surina Zhang, Kaixin Deng, Wen-Zhen Yu, Wenqian Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
diabetic retinopathy
safranal
high glucose
transcriptomics
human retinal microvascular endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.945446/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.945446/full

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