HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD.

HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD.

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Airway epithelial damage is a common feature in respiratory diseases such as COPD and has been suggested to drive inflammation and progression of disease. These features manifest as remodeling and destruction of lung epithelial characteristics including loss of small airways which contributes to chr...

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Bibliographic Details
Main Authors: Jenny Horndahl, Rebecka Svärd, Pia Berntsson, Cecilia Wingren, Jingjing Li, Suado M Abdillahi, Baishakhi Ghosh, Erin Capodanno, Justin Chan, Lena Ripa, Annika Åstrand, Venkataramana K Sidhaye, Mia Collins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0266310

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https://doi.org/10.1371/journal.pone.0266310

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