Effect and mechanism of Dichloroacetate in the treatment of stroke and the resolution strategy for side effect

Abstract Stroke is a serious disease that leads to high morbidity and mortality, and ischemic stroke accounts for more than 80% of strokes. At present, the only effective drug recombinant tissue plasminogen activator is limited by its indications, and its clinical application rate is not high. There...

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Bibliographic Details
Main Authors: Xu Wang, Chunshu Rong, Wei Leng, Ping Niu, Ziqiao He, Gaihua Wang, Xin Qi, Dexi Zhao, Jinhua Li
Format: Article
Language:English
Published: BMC 2025-03-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02399-5