Estimation and inference for the mediation effect in a time-varying mediation model

Abstract Background Traditional mediation analysis typically examines the relations among an intervention, a time-invariant mediator, and a time-invariant outcome variable. Although there may be a total effect of the intervention on the outcome, there is a need to understand the process by which the...

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Bibliographic Details
Main Authors: Xizhen Cai, Donna L. Coffman, Megan E. Piper, Runze Li
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:https://doi.org/10.1186/s12874-022-01585-x