Characterization of an <i>Mtbp</i> Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model

Characterization of an <i>Mtbp</i> Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model

MTBP is implicated in cell cycle progression, DNA replication, and cancer metastasis. However, the function of MTBP remains enigmatic and is dependent on cellular contexts and its cellular localization. To understand the in vivo physiological role of MTBP, it is important to generate <i>Mtbp&l...

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Bibliographic Details
Main Authors: Atul Ranjan, Elizabeth A. Thoenen, Atsushi Kaida, Stephanie Wood, Terry Van Dyke, Tomoo Iwakuma
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
MDM2 binding protein
MTBP
hypomorphic allele
mouse
liver cancer
migration
Online Access:https://www.mdpi.com/2072-6694/15/18/4596

Internet

https://www.mdpi.com/2072-6694/15/18/4596

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