The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice

The adipocyte hormone leptin sets the emergence of hippocampal inhibition in mice

Brain computations rely on a proper balance between excitation and inhibition which progressively emerges during postnatal development in rodent. γ-Aminobutyric acid (GABA) neurotransmission supports inhibition in the adult brain but excites immature rodent neurons. Alterations in the timing of the...

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Bibliographic Details
Main Authors: Camille Dumon, Diabe Diabira, Ilona Chudotvorova, Francesca Bader, Semra Sahin, Jinwei Zhang, Christophe Porcher, Gary Wayman, Igor Medina, Jean-Luc Gaiarsa
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-08-01
Series:eLife
Subjects:
hippocampus
chloride homeostasis
maternal obesity
KCC2
GABA
Online Access:https://elifesciences.org/articles/36726

Internet

https://elifesciences.org/articles/36726

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