METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma

Abstract Background N6-methyladenosine (m6A) is associated with mammalian mRNA biogenesis, decay, translation and metabolism, and also contributes greatly to gastrointestinal tumor formation and development. Therefore, the specific mechanisms and signaling pathways mediated by methyltransferase-like...

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Bibliographic Details
Main Authors: Zhijin Zhang, Jun Fu, Yuhao Zhang, Xianju Qin, Yuexia Wang, Chungen Xing
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-023-02844-x