Keratinocyte Biomarkers Distinguish Painful Diabetic Peripheral Neuropathy Patients and Correlate With Topical Lidocaine Responsiveness

Keratinocyte Biomarkers Distinguish Painful Diabetic Peripheral Neuropathy Patients and Correlate With Topical Lidocaine Responsiveness

This study investigated quantifiable measures of cutaneous innervation and algesic keratinocyte biomarkers to determine correlations with clinical measures of patient pain perception, with the intent to better discriminate between diabetic patients with painful diabetic peripheral neuropathy (PDPN)...

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Bibliographic Details
Main Authors: Phillip J. Albrecht, George Houk, Elizabeth Ruggiero, Marilyn Dockum, Margaret Czerwinski, Joseph Betts, James P. Wymer, Charles E. Argoff, Frank L. Rice
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Pain Research
Subjects:
neuropathic pain
keratinocytes
IENF
CGRP
sodium channels
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2021.790524/full

Internet

https://www.frontiersin.org/articles/10.3389/fpain.2021.790524/full

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