Glycation Interferes with the Expression of Sialyltransferases in Meningiomas

Glycation Interferes with the Expression of Sialyltransferases in Meningiomas

Meningiomas are the most common non-malignant intracranial tumors and prefer, like most tumors, anaerobic glycolysis for energy production (Warburg effect). This anaerobic glycolysis leads to an increased synthesis of the metabolite methylglyoxal (MGO) or glyoxal (GO), which is known to react with a...

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Bibliographic Details
Main Authors: Philipp Selke, Kaya Bork, Tao Zhang, Manfred Wuhrer, Christian Strauss, Rüdiger Horstkorte, Maximilian Scheer
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
intracranial tumor
methylglyoxal
MGO
sialylation
tumorigenesis
posttranslational modification
Online Access:https://www.mdpi.com/2073-4409/10/12/3298

Internet

https://www.mdpi.com/2073-4409/10/12/3298

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