A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions

Abstract Protein kinases play an important role in cellular signaling pathways and their dysregulation leads to multiple diseases, making kinases prime drug targets. While more than 500 human protein kinases are known to collectively mediate phosphorylation of over 290,000 S/T/Y sites, the activitie...

Full description

Bibliographic Details
Main Authors: Stefanie Jehle, Natalia Kunowska, Nouhad Benlasfer, Jonathan Woodsmith, Gert Weber, Markus C Wahl, Ulrich Stelzl
Format: Article
Language:English
Published: Springer Nature 2022-03-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.15252/msb.202110820