A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions
Abstract Protein kinases play an important role in cellular signaling pathways and their dysregulation leads to multiple diseases, making kinases prime drug targets. While more than 500 human protein kinases are known to collectively mediate phosphorylation of over 290,000 S/T/Y sites, the activitie...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2022-03-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.15252/msb.202110820 |