Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency

Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency

Summary: Rabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid cytotoxicity of first-generation (ΔG) vectors limi...

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Bibliographic Details
Main Authors: Lei Jin, Heather A. Sullivan, Mulangma Zhu, Nicholas E. Lea, Thomas K. Lavin, Xin Fu, Makoto Matsuyama, YuanYuan Hou, Guoping Feng, Ian R. Wickersham
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports: Methods
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237523003156

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http://www.sciencedirect.com/science/article/pii/S2667237523003156

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