Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Denosumab Can Prevent Collapse in Patients with Early‐Stage Steroid‐Induced Osteonecrosis of the Femoral Head by Inhibiting Osteoclasts and Autophagy

Objective The osteoclastic bone resorption inhibitors might have positive effect in preventing femoral head collapse in patients with osteonecrosis of the femoral head (ONFH). However, as a novel osteoclastic inhibitor, whether denosumab can prevent collapse in steroid‐induced ONFH remains unknown....

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Bibliographic Details
Main Authors: Bo Liu, Feng Gao, Xiaofei Xiu, Tao Wu, Zeming Liu, Bingshi Zhang, Sikai Liu, Yongtai Han
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Orthopaedic Surgery
Subjects:
Autophagy
Collapse
Denosumab
Osteoclast
Osteonecrosis
Online Access:https://doi.org/10.1111/os.13584

Internet

https://doi.org/10.1111/os.13584

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