CXCR2 Receptor: Regulation of Expression, Signal Transduction, and Involvement in Cancer

Chemokines are a group of about 50 chemotactic cytokines crucial for the migration of immune system cells and tumor cells, as well as for metastasis. One of the 20 chemokine receptors identified to date is CXCR2, a G-protein-coupled receptor (GPCR) whose most known ligands are CXCL8 (IL-8) and CXCL1...

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Bibliographic Details
Main Authors: Jan Korbecki, Patrycja Kupnicka, Mikołaj Chlubek, Jarosław Gorący, Izabela Gutowska, Irena Baranowska-Bosiacka
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/4/2168