Human pluripotent stem cell-derived brain organoids as in vitro models for studying neural disorders and cancer

Abstract The sheer complexities of brain and resource limitation of human brain tissue greatly hamper our understanding of the brain disorders and cancers. Recently developed three-dimensional (3D) brain organoids (BOs) are self-organized and spontaneously differentiated from human pluripotent stem...

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Bibliographic Details
Main Authors: Juan Luo, Peng Li
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00617-1