Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota.

The human gastrointestinal tract harbours a complex microbial community which exist in planktonic and sessile form. The degree to which composition and function of faecal and mucosal microbiota differ remains unclear. We describe the development and characterisation of an in vitro human gut model, w...

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Bibliographic Details
Main Authors: Grace S Crowther, Caroline H Chilton, Sharie L Todhunter, Scott Nicholson, Jane Freeman, Simon D Baines, Mark H Wilcox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3916432?pdf=render