Mutant dlx3b disturbs normal tooth mineralization and bone formation in zebrafish

Background Tricho-dento-osseous (TDO) syndrome is an autosomal dominant disorder characterized by anomalies in hair, teeth and bone (OMIM190320). Various mutations of Distal-Less 3 (DLX3) gene are found to be responsible for human TDO. The aim of this study was to investigate effects of DLX3 on toot...

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Bibliographic Details
Main Authors: Liping Pang, Zhichun Zhang, Yan Shen, Zhenchao Cheng, Xuejun Gao, Bo Zhang, Xiaoyan Wang, Hua Tian
Format: Article
Language:English
Published: PeerJ Inc. 2020-02-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/8515.pdf