Melatonin blunted the angiogenic activity in 3D colon cancer tumoroids by the reduction of endocan

Abstract Background Complexity and heterogeneity of the tumor niche are closely associated with the failure of therapeutic protocols. Unfortunately, most data have been obtained from conventional 2D culture systems which are not completely comparable to in vivo microenvironments. Reconstructed 3D cu...

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Bibliographic Details
Main Authors: Maryam Taghavi Narmi, Hanieh Mohajjel Shoja, Sanya Haiaty, Mahdi Mahdipour, Reza Rahbarghazi
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02951-5