Melatonin blunted the angiogenic activity in 3D colon cancer tumoroids by the reduction of endocan
Abstract Background Complexity and heterogeneity of the tumor niche are closely associated with the failure of therapeutic protocols. Unfortunately, most data have been obtained from conventional 2D culture systems which are not completely comparable to in vivo microenvironments. Reconstructed 3D cu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-06-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-023-02951-5 |