Memantine and Riluzole Exacerbate, Rather Than Ameliorate Behavioral Deficits Induced by 8-OH-DPAT Sensitization in a Spatial Task
Chronic sensitization to serotonin 1A and 7 receptors agonist 8-OH-DPAT induces compulsive checking and perseverative behavior. As such, it has been used to model obsessive-compulsive disorder (OCD)-like behavior in mice and rats. In this study, we tested spatial learning in the 8-OH-DPAT model of O...
Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
MDPI AG
2021-07-01
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coleção: | Biomolecules |
Assuntos: | |
Acesso em linha: | https://www.mdpi.com/2218-273X/11/7/1007 |