Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene

Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients caused by heterozygous mutations in the HCN4 gene

Dilated cardiomyopathy (DCM) is a progressive heart muscle disease that can culminate with heart failure and death. Mutations in several genes can cause DCM, including hyperpolarization-activated cyclic nucleotide-gated channel (HCN4), which has a critical function in the autonomic control of the he...

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Bibliographic Details
Main Authors: Zehra Yildirim, Ana Kojic, Christopher D. Yan, Matthew A. Wu, Randall Vagelos, Joseph C. Wu
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Stem Cell Research
Subjects:
Dilated cardiomyopathy
iPSC
Stem cells
HCN4
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506122003002

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http://www.sciencedirect.com/science/article/pii/S1873506122003002

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